Intensive insulin therapy during cardiovascular surgery

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Intensive insulin therapy to maintain normoglycemia after cardiac surgery

Drugs used in the perioperative period could have an effect on survival as recently pointed out by an international consensus conference on the reduction in mortality in cardiac anesthesia and intensive care. Insulin infusion to achieve a strict glycemic control is the best example of how an ancillary (i.e. non-surgical) drug/technique/strategy might influence survival rates in patients undergo...

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How Intensive Insulin Therapy May Benefit Cardiac Surgery Patients

Interest in the effects of insulin on the heart came with the recognition that hyperglycemia in the context of myocardial infarction is associated with increased risks of mortality, congestive heart failure, or cardiogenic shock.1–3 More recently, instigated by research findings on stress hyperglycemia in critical illness, this interest has been extended to the influence of insulin on clinical ...

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Contemporary Reviews in Cardiovascular Medicine Cardioprotective Effects of Insulin How Intensive Insulin Therapy May Benefit Cardiac Surgery Patients

Interest in the effects of insulin on the heart came with the recognition that hyperglycemia in the context of myocardial infarction is associated with increased risks of mortality, congestive heart failure, or cardiogenic shock.1–3 More recently, instigated by research findings on stress hyperglycemia in critical illness, this interest has been extended to the influence of insulin on clinical ...

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Intensive intraoperative insulin therapy versus conventional glucose management during cardiac surgery.

BACKGROUND It is not known whether rigorous intraoperative glycemic control reduces death and morbidity in cardiac surgery patients. OBJECTIVE To compare outcomes of intensive insulin therapy during cardiac surgery with those of conventional intraoperative glucose management. DESIGN A randomized, open-label, controlled trial with blinded end point assessment. SETTING Tertiary care center....

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Analysis: Continuous glucose monitoring during intensive insulin therapy.

Results of the Normoglycemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation (NICE-SUGAR) trial, intensive insulin therapy (IIT), and use of a continuous glucose sensor in intensive care units (ICU) were analyzed. The NICE-SUGAR trial was unable to determine if optimal intensive insulin therapy decreases mortality. Continuous glucose monitoring (CGM) technology has ...

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ژورنال

عنوان ژورنال: The Journal of Medical Investigation

سال: 2010

ISSN: 1343-1420,1349-6867

DOI: 10.2152/jmi.57.191